June 25, 2024

Check out our recent paper on bioRxiv that found that islet-reactive B cells from Stage 1, 2, and 3 T1D donors are enriched in polyreactivity and have a unique gene expression profile and BCR repertoire compared to high-risk first-degree relatives!

Link to paper: Islet-antigen reactive B cells display a unique phenotype and BCR repertoire in autoantibody positive and recent-onset type 1 diabetes patients | bioRxiv